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Genetics and Molecular Biology
Biomedical Science A-209
1960 East-West Road
Honolulu, HI 96822
Tel: (808) 956-8552
Fax: (808) 956-9530
Faculty
*J. S. Bertram, PhD-carcinogenesis, growth regulation and chemoprevention of cancer
panic and depression; gender differences in emotional behavior
*D. C. Blanchard, PhD-ethoexperimental analysis of defense and aggression; preclined pharmacoethology of anxiety,
*J. L. Brewbaker, PhD-horticultural genetics
*G. D. Bryant-Greenwood, PhD-preterm birth in the human, role of relaxins in fetal membrane rupture
*R. L. Cann, PhD-molecular and evolutionary genetics
*F. C. Greenwood, PhD-biochemical endocrinology, measurement and metabolism of protein hormones, particularly relaxin
*D. S. Haymer, PhD-molecular evolution and developmental genetics
*Y. E. Hsia, MD-medical genetics
*T. D. Humpreys II, PhD-molecular biology of development
*J. A. Hunt, PhD-molecular and evolutionary genetics
*D. M. Jameson, PhD-fluorescence spectroscopy; biomolecular dynamics and interactions; ribosomal proteins
*A. F. Lau, PhD-molecular biology of cancer
*T. W. Lyttle, PhD-population genetics, cytogenetics
B. R. Powell, MD-human genetics
*M. D. Rayner, PhD-structure-function relationships in voltage-gated ion channels
*J. F. Scott, PhD-molecular biology of DNA
*S. E. Seifried, PhD-macromolecular interactions, transcription factor recognition of specific DNA sequences, protein subunit assembly
Adjunct Faculty
T. A. Donlon, PhD-human genetics
A. Fleig, PhD-electrophysiology (patch-clamp); calcium signaling in muscle cells; regulation of calcium signaling; cellular neuroimmunology
R. Penner, PhD-electrophysiology (patch-clamp); intra- and intercellular signal transduction; regulation of calcium signaling; cellular neuroimmunology
*Graduate Faculty
Degrees Offered: MS in biomedical science (genetics), PhD in biomedical science (genetics)
The Academic Program
The department offers the MS and PhD degrees in biomedical science (genetics) with concentrations in the areas of human and evolutionary genetics, molecular and cell genetics, and population and evolutionary genetics. Intended candidates for the MS degree must have or acquire adequate preparation in biology, calculus, chemistry through organic chemistry, physics, and genetics. Additional preparation will depend upon the area of genetics in which the candidate wishes to specialize. For population and statistical genetics, an adequate mathematical background is advisable. For molecular genetics, organic chemistry and biochemistry are desirable.
Students pursuing an MS in biomedical sciences (genetics) fall into two categories, depending on whether they opt for a Plan A (thesis) or Plan B (non-thesis) master's degree. The MS Plan B is usually a terminal degree, appropriate for professionals in primary and secondary education, nursing, medical technology, government, and related fields who wish to obtain broad training in modern genetics to advance their credentials in their chosen fields. The MS Plan A serves as a qualifying examination for students who intend to continue toward the PhD in any of several biomedical sciences degree programs, particularly genetics. It may also serve as a terminal degree for those who wish to pursue careers as research technicians, either in the public or private sector. Those who seek the PhD degree usually wish to make a career in college and university teaching and research, in research for industry and government, or in medicine, dentistry, or medical technology.
All students registered for graduate degrees in genetics are expected to participate in GENE 654 each semester. In order to develop skills and basic genetic knowledge necessary for interaction with students in both discussion and laboratory settings, degree candidates are required to assist in the department's undergraduate curriculum. MS and PhD candidates must assist in at least one course.
Advising
Complete details about the graduate programs and faculty in genetics, as well as financial aid available to prospective students, may be obtained upon request from the department.
Graduate Study
Master's Degree
Prospective MS candidates may choose either the Plan A (thesis) or Plan B (non-thesis) programs. Plan A is taken by students wishing to proceed to the PhD degree. The Plan B option is offered for medical students, students in the health sciences, or others who would benefit from a knowledge of genetics in their chosen fields.
Requirements
Minimum required course work for both options consists of BIOM 621 and GENE 650, 671, 672, 680, and two semesters of 654. Equivalent courses may be substituted for students concurrently enrolled in the Cellular, Molecular, and Neurosciences (CMNS) or other graduate special programs. Additional requirements for Plan A students are at least 2 credit hours of GENE 699, for which enrollment is required by no later than the fifth semester; GENE 700; any individualized course work specified by the thesis committee; and successful defense of the thesis. In lieu of a thesis, additional course requirements for Plan B are at least 6 credit hours of further course work chosen from the department's graduate courses; GENE 699 (6 credit hours); and successful presentation of both oral and written reports on the directed research project to the program committee.
Doctoral Degree
Intended candidates for the PhD degree are expected to possess an MS Plan A degree in genetics or its equivalent. PhD candidates must have demonstrated a potential for undertaking original research in genetics.
Requirements
Formal course requirements for the PhD, beyond completion of the requirements for the MS Plan A option or equivalent are GENE 654 (two semesters), GENE 699 (enrollment required by the third semester), GENE 800, and any additional courses specified by the dissertation committee.
Medical History
Biomedical Science T-101
1960 East-West Road
Honolulu, HI 96822
Tel: (808) 956-8287
Fax: (808) 956-5506
The Division of Medical History (MDHX) examines the general area of medical history, particularly that of the Pacific and Asia. It is strengthened by a growing collection of material in the Hawai'i Medical Library.
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