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Biomedical Sciences (BIOM)

School of Medicine

BIOM 499 Directed Research and Reading (V) To provide elective courses for undergraduates in the biomedical sciences specialties. Repeatable unlimited times.

BIOM 500 Master's Plan B/C Studies (1) Repeatable unlimited times.

BIOM 601 Global Health and Medicine: Emerging Problems and Impact (3) Analysis of emerging problems and impact in countries on a multidimensional perspective. Repeatable one time. BIOM, NURS, PH, SPA majors only. Pre: consent.

BIOM 640 Clinical Research Methods (2) Instruction in developing clinical research questions and creating a concise protocol that includes a literature review, study design, subject recruitment and sampling, instruments, other measures and bioinformatics, sample size, consent form, budget and timetable. A-F only. Pre: consent.

BIOM 641 Legal and Regulatory Issues and Bioethics (2) Ethical dilemmas in clinical research are identified and resolved in cases, research on human subjects regulation are discussed. Research misconduct is defined. Ethical considerations in protocol developed in the Designing Clinical Research course are resolved. A-F only. (Cross-listed as CMB 626)

BIOM 642 Applied Clinical Epidemiology and Biostatistics (3) Introductory epidemiologic and intermediate biostatistical methods are applied to clinical research. Epidemiologic measures such as relative risks and odds ratios and how to interpret these measures in the context of clinical studies will be addressed. Interpretation of screening tests will be included. A-F only. Pre: 640 and consent.

BIOM 643 Applied Biostatistics (3) Combines a didactic approach to multivariable regression with hands-on analysis of a clinical dataset. Regression methods for normally distributed, binary and count data, time-to-event data, model building and model evaluation are included. A-F only. Pre: 640, 642, or consent.

BIOM 644 Bioanalytical Methods (2) Introduction to disease molecular genetics: methods to identify and map candidate genes, analysis of mutations, use of markers, evaluation of gene and protein expression, collection methods, preparation of specimens, and extraction of DNA and proteins. A-F only. Pre: consent.

BIOM 645 Clinical Protocol Development (3) Provides training in proposal development. Governance structures of funding agencies; funding opportunities and decisions; review processes; NIH application and processes; reading RFAs; compliance issues; cultural sensitivity; and types of questions using databases are addressed. A-F only. Pre: consent.

BIOM 646 Clinical Research Seminar (1) Provides overview of research related to health and health disparities in Hawai'i. Seminar topics include ethnic disparities in health research, Native Hawaiian health, childhood research initiatives, fitness and obesity, social and cultural factors and ethics. Repeatable six times. A-F only. Pre: consent.

BIOM 647 Cultural Competence in Biomedical Research I (3) Introductory lecture-seminar on the conduct of multidisciplinary research from a culturally competent perspective. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 648 Foundations of Biomedical Ethics (3) Explores the foundations of biomedical ethics via small group seminars and discussion, presentations. Enrolled in MS or PhD in Biomedical Sciences program only. A-F only. (Alt. years)

BIOM 649 Advanced Ethics in Biomedical Research II (3) Develop biomedical ethics through case studies to incite discussions on topics such as gene therapy, gene enhancement, genetic counseling, informed consent, health care professional/patient and investigator/student participant communication, advanced directives and living wills, clinical research in developing countries, clinical research in ethnic minority and socio-economically disadvantaged populations, and non-discrimination in health care and research settings. A-F only.

BIOM 650 Cultural Competence in Biomedical Research II (3) Explore topics in cultural competence in greater depth, encouraging trainees to address issues from a unified yet flexible conceptual framework. Involves building knowledge, skills and action plans to address a range of learning styles and to appreciate and benefit from diversity. A-F only.

BIOM 651 PhD Team Building Seminar (V) Seminar focuses on teaching participants to work independently and collaborate in order to accomplish specific results. Students will be exposed to group dynamics, communication, healthy competition, conflict resolution, and innovative means of crossing boundaries between departments, organizations, industries and disciplines. Repeatable two times. A-F only.

BIOM 654 Molecular Genetics of Human Diseases (1) Present discoveries in the area of molecular genetics of human diseases, explore molecular mechanisms of pathology and discuss current concepts and innovative approaches in cardiovascular, neurodegenerative and skin disorders research. Pre: consent.

BIOM 660 Mentored Research Practicum (V) Conduct research under the direction of a mentor. Participants will be responsible for submission of a proposal, acquisition of IRB approval, and conduct of the project. Repeatable five times or up to 12 credits. BIOM students only. A-F only.

BIOM 667 Advanced Biostatistics for Clinical Research (3) Current methods for analyzing longitudinal and clustered, clinical data through lectures, discussions, and a group analysis. Topic areas include multi-level, multi-state, multi-process, and structural equation models. A-F only. Pre: 642 and 643, or consent.

BIOM 699 Directed Reading (V) Students may register on approval of department. CR/NC only. Repeatable unlimited times.

BIOM 700 Thesis Research (V) Research for master's thesis. Repeatable unlimited times. CR/NC only. Pre: consent.

BIOM 701 Disasters and Pandemics: Medical and PH Management and Risk Communication (3) Assess impact on health in disasters and diseases. Enhances research skills related to management and communication. Repeatable one time. BIOM, PH, NURS, and SPA majors only. Pre: consent.

BIOM 800 Dissertation Research (V) Research for doctoral dissertation. Repeatable unlimited times. CR/NC only. Pre: consent.